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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272351Generated: November 4, 2026

Hydrochloric Acid → HCID 18456050, compound

https://huagongshe.com/reaction/1272351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBenzyl ChlorideHCID 7503—
ReactantHCID 22935611HCID 22935611—
SolventEthyl AcetateHCID 8857—
ProductHCID 18456050HCID 1845605064%

Reaction Steps

Using Benzyl chloride and (2,2,4,6,7-pentamethyl-3-piperidino-2,3-dihydro-1-benzofuran-5-yl)piperazine obtained in Example 152, the free base was obtained in the same manner as in Example 2. The free base was treated with a 4 N hydrogenchloride in ethyl acetate solution (10 ml) to obtain the title compound. Yield 64% Amorphous powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07208495B2
Source datasetuspto-grants-2007_04
ORD IDord-b7753cbd33af46f1b7cbd34c82489e53
Source noteuspto-grants-2007_04