Salicylic Acid → HCID 10042140, compound

HRID 1272447Notes

Reaction equation

HRID 1272447 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[NH:9][C:10]2[C:15]([CH:16]=1)=[CH:14][CH:13]=[CH:12][CH:11]=2.[C:17](O)(=[O:25])[C:18]1[C:19](=[CH:21][CH:22]=[CH:23][CH:24]=1)[OH:20]>>[OH:20][C:19]1[CH:21]=[CH:22][CH:23]=[CH:24][C:18]=1[C:17]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[NH:9][C:10]2[C:15]([CH:16]=1)=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:25]

Participants

3

Reactant 2

HCID 338Salicylic AcidHCID 7359662-(2-Aminophenyl)indole

Product 1

HCID 10042140HCID 10042140, compoundYield 46%

Procedure

Prepared from 2-(2-aminophenyl) indole and salicylic acid in 46% yield following procedure 1. The compound was chromatographed on silica using an ethylacetate/hexane gradient. % Purity by LC/MS (230 DAD), Mass-spec (M+H+)=329, 1H NMR (MeOH-d4): 6.66 s (1H), 6.86 dd,

Workup

  1. customThe compound was chromatographed on silica using an ethylacetate/hexane gradient

Sources & evidence

ORD record
ord-858e01bba0514e39ba706a0e27330cc0
Source dataset
uspto-grants-2007_04
Patent number
US07208493B2

Reaction notes

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