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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 127247Generated: October 27, 2026

1-Chloro-4-(chloromethyl)benzene → 1-(4-Chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

https://huagongshe.com/reaction/127247

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-(chloromethyl)benzeneHCID 7723—
Reactant1-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037790—
Product1-(4-Chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037793—

Reaction Steps

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 4-chlorobenzylchloride to form 1-(4-chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 237°-239° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04255426
Source datasetuspto-grants-1981_03
ORD IDord-cba2737f6dda4ea18c3edc6c3a02b8c9
Source noteuspto-grants-1981_03