Propylamine → HCID 21922955, compound

HRID 1272626Notes

Reaction equation

HRID 1272626 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][O:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[CH2:17]([NH2:20])[CH2:18][CH3:19]>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][O:13][CH2:12]2)=[C:4]([NH:20][CH2:17][CH2:18][CH3:19])[N:3]=1

Participants

4

Reactant 2

HCID 7852PropylamineHCID 21923063HCID 21923063, compound

Product 1

HCID 21922955HCID 21922955, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The operation is carried out as in Stage 2 of Example 2 starting from 181 mg of the product obtained in Stage 1 of Example 2 and 3 ml of butanol and using 0.062 ml of 1-propanamine in place of the benzylamine. In this way 136 mg of expected product is obtained in the form of beige crystals.

Sources & evidence

ORD record
ord-d388e753b4a746389ca2f160f6e0551b
Source dataset
uspto-grants-2007_04
Patent number
US07208598B2

Reaction notes

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