HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272715Generated: November 3, 2026
Pyrrolidine → 2-Amino-5-pyrrol-1-yl-1,3,4-thiadiazole
https://huagongshe.com/reaction/1272715
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 5-Chloro-1,3,4-thiadiazol-2-amine | HCID 314235 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-5-pyrrol-1-yl-1,3,4-thiadiazole | HCID 18457789 | — |
Reaction Steps
Pyrrolidine (200 μl) was added to a solution of 2-amino-5-chloro-1,3,4-thiadiazole (60 mg) in ethanol (2 ml) and the mixture heated in a sealed vial at 40° C. for 6 hours. The precipitate was filtered off and washed with a little methanol to give 2-amino-5-pyrrol-1-yl-1,3,4-thiadiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07208629B2 |
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| Source dataset | uspto-grants-2007_04 |
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| ORD ID | ord-92e5e25105d84f3d9a06d72b5f55d842 |
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| Source note | uspto-grants-2007_04 |
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