HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 20286680, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 21829635 | HCID 21829635 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 20286680 | HCID 20286680 | — |
Reaction Steps
Add 1.0 ml of bromine to 4.6 g of ethyl 5-chloro-3-(2-fluorophenyl)indole-2-carboxylate in 250 ml of glacial acetic acid. Stir for 16 hours at room temperature, add water and collect the precipitate. Ws the precipitate with warm methanol. Collect the dry ethyl 6-bromo-5-chloro-3-(2-fluorophenyl)indole-2-carboxylate, m.p. 193°-194°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255442 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-53f6f81270b145c990fcf2571f79ce83 |
| Source note | uspto-grants-1981_03 |