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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273114Generated: November 2, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273114

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
Reagent2,6-LutidineHCID 7937—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178487187HCID 1784871870.21%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-762f05737bdd4e21b2d7dc3ca54610ec
Source noteAniline amide coupling reaction