Methylamine → AH 18801

HRID 127328Notes

Reaction equation

HRID 127328 reaction equation
[C:1]([N:3]=[C:4](SC)[NH:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[O:11][C:12]([CH2:15][N:16]([CH3:18])[CH3:17])=[CH:13][CH:14]=1)#[N:2].[CH3:21][NH2:22]>>[C:1]([NH:3][C:4]([NH:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[O:11][C:12]([CH2:15][N:16]([CH3:18])[CH3:17])=[CH:13][CH:14]=1)=[N:22][CH3:21])#[N:2]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 178503926HCID 178503926, compound

Product 1

HCID 182530AH 18801

Procedure

A solution of N'-cyano-N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]carbamimidothioic acid, methyl ester (1.06 g) in ethanolic methylamine 33% (10 ml) was stirred at room temperature for 4 hr. The solution was evaporated to dryness and the oily residue crystallised from ethyl acetate-light petroleum (b.p. 80°-100°) to give the title compound m.p. 77°-80°.

Workup

  1. customThe solution was evaporated to dryness
  2. customthe oily residue crystallised from ethyl acetate-light petroleum (b.p. 80°-100°)

Sources & evidence

ORD record
ord-21b63263f4a040d6b50257c0d12d8201
Source dataset
uspto-grants-1981_03
Patent number
US04255440

Reaction notes

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