Isopropanol → HCID 18398302, compound

HRID 127339Notes

Reaction equation

HRID 127339 reaction equation
[Cl-].[NH4+].C(O)(C)C.[CH3:7][O:8][C:9]1[CH:14]=[C:13]([O:15][CH3:16])[C:12]([N+:17]([O-])=O)=[CH:11][C:10]=1[S:20]([OH:23])(=[O:22])=[O:21]>O>[CH3:7][O:8][C:9]1[CH:14]=[C:13]([O:15][CH3:16])[C:12]([NH2:17])=[CH:11][C:10]=1[S:20]([OH:23])(=[O:22])=[O:21]

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 25517Ammonium ChlorideHCID 20286805HCID 20286805, compound

Product 1

HCID 18398302HCID 18398302, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture solution prepared by adding 15 g of reduced iron, 0.3 g of ammonium chloride and 50 ml of isopropyl alcohol to 10 g of 2,4-dimethoxy-5-nitrobenzenesulfonic acid obtained in Step (2) above, was heated at 70° to 80° C. on a water bath with stirring, and 50 ml of water was added thereto. After stirring at 80° C. for 1 hour, the mixture was filtered while hot. To the filtrate, 20 ml of hydrochloric acid (d=1.18) was added. The crystals thus-precipitated were collected by filtration and washed with 20 ml of iropropyl alcohol.

Workup

  1. customA mixture solution prepared
  2. temperaturewas heated at 70° to 80° C. on a water bath
  3. stirringAfter stirring at 80° C. for 1 hour
  4. filtrationthe mixture was filtered while hot
  5. additionTo the filtrate, 20 ml of hydrochloric acid (d=1.18) was added
  6. customThe crystals thus-precipitated
  7. filtrationwere collected by filtration
  8. washwashed with 20 ml of iropropyl alcohol

Sources & evidence

ORD record
ord-7e74e366c84843efad0bbee3a7bcb035
Source dataset
uspto-grants-1981_03
Patent number
US04255509

Reaction notes

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