Indomethacin → HCID 178487184, compound
Reaction equation
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1.Cc1cc(C)c(N)c(Br)c1>CC#N.Cc1cccc(C)n1.O=C1OCCN1P(=O)(Cl)N1CCOC1=O>COc1ccc2c(c1)c(CC(=O)Nc1c(C)cc(C)cc1Br)c(C)n2C(=O)c1ccc(Cl)cc1Participants
6
Conditions
- Temperature
- 25 °C
Workup
- additiondilution
- stirringNo procedure recorded
- aliquotNo procedure recorded
- additiondilute aliquot with HPLC solvents
- filtrationfilter for UPLC-MS · Keep liquid (mobile)
Sources & evidence
- ORD record
- ord-8454c4691e114db1862d78a6f4c6c0fe
- Source dataset
- Aniline amide coupling reaction
- Original link
- View source
Reaction notes
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