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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273608Generated: October 28, 2026

Indomethacin → HCID 178487189, compound

https://huagongshe.com/reaction/1273608

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Methyl-4-nitroanilineHCID 7441—
ReagentDiisopropylethylamineHCID 81531—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178487189HCID 1784871893.77%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-92c4a27008584b11b8a56fe82268924a
Source noteAniline amide coupling reaction