HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-(Propylthio)pyrimidine-4,6-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | HCID 178516656 | HCID 178516656 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(Propylthio)pyrimidine-4,6-diol | HCID 178460810 | — |
Reaction Steps
Propyl iodide (136 ml) was added to a suspension of 4,6-dihydroxy-2-mercaptopyrimidine (200 g) in water (800 ml), containing sodium hydroxide (55.6 g). The reaction mixture was stirred for 2 weeks then concentrated to half volume, 2N hydrochloric acid added and the product isolated by filtration (167 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06156756 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-e0112a49ba2b42f480dbd187de6f84ea |
| Source note | uspto-grants-2000_12 |