HCID 22120830, compound → HCID 22120826, compound

HRID 1274231Notes

Reaction equation

HRID 1274231 reaction equation
C([O:3][C:4](=[O:34])[CH:5]([C:23]1[S:24][C:25]([CH2:28][N:29]2[N:33]=[CH:32][CH:31]=[N:30]2)=[CH:26][CH:27]=1)[NH:6][C:7](=[O:22])[CH:8]([CH2:17][S:18]C(=O)C)[CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)C>C(Cl)(Cl)Cl>[N:33]1[N:29]([CH2:28][C:25]2[S:24][C:23]([CH:5]([C:4]([OH:34])=[O:3])[NH:6][C:7](=[O:22])[CH:8]([CH2:17][SH:18])[CH2:9][CH2:10][C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=3)=[CH:27][CH:26]=2)[N:30]=[CH:31][CH:32]=1

Participants

3

Reactant 1

HCID 22120830HCID 22120830, compound

Product 1

HCID 22120826HCID 22120826, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared from 2-[5-(1,2,3-triazol-2-ylmethyl)thien-2-yl]-N-[2-(acetylthiomethyl)-4-phenylbutyryl]glycine ethyl ester by (Description 59) the procedure described in Example 29. vmax (CHCl3) 3289 and 1621 cm-1. δ (CD3SOCD3) 1.68-1.83 (2H, m), 2.44-2.73 (5H, m), 5.20 (1H, d, J 6.87 Hz), 5.73 (2H, s), 6.83-6.94 (2H, m), 7.10-7.30 (5H, m), 7.74 and 7.78 (2H, two s's), 8.10 (1H, d, J 7.07 Hz). m/z 431 (MH+).

Sources & evidence

ORD record
ord-25a151ceda0a46128889879813357c03
Source dataset
uspto-grants-2000_12
Patent number
US06156774

Reaction notes

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