4-Methylbenzyl chloride → HCID 23665764, compound

HRID 1274265Notes

Reaction equation

HRID 1274265 reaction equation
[S:1]([O-:4])([O-:3])=[O:2].[Na+:5].[Na+].[CH3:7][C:8]1[CH:15]=[CH:14][C:11]([CH2:12]Cl)=[CH:10][CH:9]=1>O>[Na+:5].[CH3:7][C:8]1[CH:15]=[CH:14][C:11]([CH2:12][S:1]([O-:4])(=[O:3])=[O:2])=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 77224-Methylbenzyl chlorideHCID 24437Sodium Sulfite

Product 1

HCID 23665764HCID 23665764, compoundYield 461.5%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of sodium sulfite (14.3 g, 113 mmol) in water (60 mL) was added 4-methylbenzyl chloride (15.0 mL, 1 13 mmol). The mixture was stirred under reflux for 12 hours, and cooled to rt. The precipitate was collected by filtration, and washed with water and ether to give 4-methylphenylmethanesulfonic acid sodium salt (12.5 g, 60 mmol, 53%).

Workup

  1. temperatureunder reflux for 12 hours
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with water and ether

Sources & evidence

ORD record
ord-a4e123f82dca4516ab1b9f599db909ad
Source dataset
uspto-grants-2000_12
Patent number
US06156784

Reaction notes

Loading…