Dodecylamine → HCID 20287139, compound

HRID 127475Notes

Reaction equation

[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[ClH:14].CC(C)(C)CN[C:19](=[O:43])[C:20]1[CH:25]=[C:24]([CH:26]([OH:41])[CH2:27][N:28]2[CH2:33][CH2:32][N:31]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[CH3:40])[CH2:30][CH2:29]2)[CH:23]=[CH:22][C:21]=1[OH:42]>>[ClH:14].[CH2:1]([NH:13][C:19](=[O:43])[C:20]1[CH:25]=[C:24]([CH:26]([OH:41])[CH2:27][N:28]2[CH2:29][CH2:30][N:31]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[CH3:40])[CH2:32][CH2:33]2)[CH:23]=[CH:22][C:21]=1[OH:42])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

Reactant 2

HCID 13583Dodecylamine

HCID 20287072N-(2,2-dimethylpropyl)-2-hydroxy-5-[1-hydroxy-2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]benzamide monohydrochloride

Product 1

HCID 20287139HCID 20287139, compound

Procedure

Following essentially the same procedure but substituting dodecylamine for the neopentylamine above results in the preparation of N-dodecyl-2-hydroxy-5-[1-hydroxy-2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]benzamide hydrochloride.

Sources & evidence

ORD record: ord-cd5de87adc664514a78812db4d9ff94a
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04255575

Reaction notes

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