Hydrochloric Acid → HCID 21249820, compound

Participants

Reaction Conditions

Reaction Steps

5-methoxy-6-[3-(trifluoromethyl)phenoxy] picolinic acid picolinic acid methyl ester (0.7 g, 0.0021 mol) was dissolved in 2.8 ml of ethyl alcohol. One milliliter of an aqueous solution of sodium hydroxide (0.102 g, 0.0021×1.2 mol) was added to the obtained solution. The resultant mixture was heated and stirred at 70° C. for 1.5 hours. After cooling, the obtained reaction solution was mixed with 2 ml of concentrated hydrochloric acid, thereby precipitating solids. The precipitated solids were filtered out from the solution, washed with water and then dried.

Provenance & Evidence