1-(2-Aminoethyl)-4-(2-methoxyphenyl)piperazine → HCID 9846831, compound

Participants

Reaction Steps

1.9 g (8.0 mM [sic]) of 1-(2-aminoethyl)-4-(2-methoxyphenyl)-piperazine were added to 2.4 g (7.8 mM [sic]) of 2-ethoxymethyleneamino-3-carboethoxy-4-methyl-5-dimethylcarbamoyl thiophene in 30 ml of ethanol and refluxed for 2 h. The product crystallized out after standing overnight and was filtered off with suction and washed with a little ethanol. 2.2 g (62%) of product were isolated with melting point 188-190° C.

Provenance & Evidence