反应详情

To a solution of 140 mg of thiourea in ethanol (3 ml), 300 mg of 5-chloro-6-chloromethyluracil were added, followed by heating for 6 hours under reflux. After the reaction mixture was allowed to cool down, a crystallized matter was collected by filtration, whereby 337 mg of the title compound were obtained (yield: 81%).

1. temperatureby heating for 6 hours
2. temperatureunder reflux
3. temperatureto cool down
4. filtrationa crystallized matter was collected by filtration