HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → HCID 21699321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 5-Chloro-6-(chloromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione | HCID 4171056 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21699321 | HCID 21699321 | 161.6% |
Reaction Steps
To a solution of 140 mg of thiourea in ethanol (3 ml), 300 mg of 5-chloro-6-chloromethyluracil were added, followed by heating for 6 hours under reflux. After the reaction mixture was allowed to cool down, a crystallized matter was collected by filtration, whereby 337 mg of the title compound were obtained (yield: 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06159969 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-e1e4c92caa184635aa17c934869cef21 |
| Source note | uspto-grants-2000_12 |