2,6-Dichloroaniline → HCID 20284762, compound

Participants

Reaction Steps

A solution of 65 g (0.33 mols) of ethyl 2-cyclohexanone-glyoxylate and 135 g (0.83 mols) of 2,6-dichloroaniline in 150 ml of methanol is refluxed for 30 hours. After this period, there is introduced steam into the reaction vessel, thus removing the excess 2,6-dichloroaniline. The residue of the steam distillation is removed by filtration and recrystallized from methanol.

Provenance & Evidence