huagongshe.com
HRID127496

反应详情

EQUATION

反应方程式

HRID 127496 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)C[N+](=O)[O-]
HCID17206

Nitroacetic acid methyl ester

C3H5NO4

结构：Cc1ccc(C(C=O)=CN(C)C)c([N+](=O)[O-])c1
HCID53688648

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)C(=CC(=CN(C)C)c1ccc(C)cc1[N+](=O)[O-])[N+](=O)[O-]
HCID53861862

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)OC(C)=O
溶剂HCID7918

Acetic anhydride

C4H6O3

PROCEDURE

实验过程

A mixture of 67.5 g (0.29 mol) of the compound of Example 15 and 34.3 g (0.29 mol) of methyl nitroacetate in 540 ml of acetic anhydride was heated at 60° for 2 hours. The product was worked up and recrystallized from benzene-DMF (3:1) affording 75.1 g (78%) of product as red orange crystals, m.p. 213°-215°.

WORKUP

后处理

  1. temperaturewas heated at 60° for 2 hours
  2. customrecrystallized from benzene-DMF (3:1)