HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-nitroacetate → 5-Dimethylamino-2-nitro-4-[4-methyl-2-nitrophenyl]-2,4-pentadienoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-nitroacetate | HCID 17206 | — |
| Reactant | 3-Dimethylamino-2-[4-methyl-2-nitrophenyl]acrolein | HCID 53688648 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 5-Dimethylamino-2-nitro-4-[4-methyl-2-nitrophenyl]-2,4-pentadienoic acid methyl ester | HCID 53861862 | 78% |
Reaction Steps
A mixture of 67.5 g (0.29 mol) of the compound of Example 15 and 34.3 g (0.29 mol) of methyl nitroacetate in 540 ml of acetic anhydride was heated at 60° for 2 hours. The product was worked up and recrystallized from benzene-DMF (3:1) affording 75.1 g (78%) of product as red orange crystals, m.p. 213°-215°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04256641 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-322c02f2188e442ca2e0dd6c6fcd1e21 |
| Source note | uspto-grants-1981_03 |