HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-(4-methylpiperazin-1-yl)aniline → N-[4-Bromo-3-(4-methylpiperazin-1-yl)phenyl]-4-(pyridin-4-yl)naphth-1-ylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-(4-methylpiperazin-1-yl)aniline | HCID 18180099 | — |
| Reactant | 4-(Pyridin-4-yl)naphth-1-ylacetic acid | HCID 22462533 | — |
| Product | N-[4-Bromo-3-(4-methylpiperazin-1-yl)phenyl]-4-(pyridin-4-yl)naphth-1-ylacetamide | HCID 22118918 | — |
Reaction Steps
The title compound was prepared from 4-(pyridin-4-yl)naphth-1-ylacetic acid (D2) and 4-bromo-3-(4-methylpiperazin-1-yl)aniline (Intermediate 44, EP 0533268A1) using a similar procedure to Example 20 (73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06159979 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-bb94bff4b15249f8af1f2bac33adfca9 |
| Source note | uspto-grants-2000_12 |