HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-Chloropropylthio)-3-methyl-2-[(4-pyridinylthio)methyl]pyridine → 2-{5-[3-Methyl-2-[(4-pyridinylthio)methyl]-4-pyridinyl]-1,5-dithiapentyl}pyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-Chloropropylthio)-3-methyl-2-[(4-pyridinylthio)methyl]pyridine | HCID 22117302 | — |
| Reactant | HCID 178524460 | HCID 178524460 | — |
| Product | 2-{5-[3-Methyl-2-[(4-pyridinylthio)methyl]-4-pyridinyl]-1,5-dithiapentyl}pyridine-3-carboxylic acid | HCID 22117345 | 57% |
Reaction Steps
According to the procedure indicated in Example 21, reaction of 4-(3-chloropropylthio)-3-methyl-2-[(4-pyridinylthio)methyl]pyridine with 2-mercaptonicotinic acid, and subsequent establishment of a pH of about 6 gives the title compound as a colorless solid; m.p. 219° C., dec.; yield 57% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162809 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-b48e1accb3f94706acd63574ad9d9255 |
| Source note | uspto-grants-2000_12 |