2-Mercaptoethanol → HCID 22117332, compound

HRID 1275572Notes

Reaction equation

Cl[C:2]1[CH:7]=[CH:6][N+:5]([O-:8])=[C:4]([CH3:9])[C:3]=1[CH3:10].[SH:11][CH2:12][CH2:13][OH:14].[H-].[Na+]>>[CH3:9][C:4]1[C:3]([CH3:10])=[C:2]([S:11][CH2:12][CH2:13][OH:14])[CH:7]=[CH:6][N+:5]=1[O-:8]

Participants

Reactant 3

HCID 15672-Mercaptoethanol

HCID 24758Sodium hydride

HCID 98774464-Chloro-2,3-dimethyl-1-oxidopyridin-1-ium

Product 1

HCID 22117332HCID 22117332, compound

Procedure

According to the procedure indicated in Example A2. a), reaction of 4-chloro-2,3-dimethylpyridine-N-oxide with 2-mercaptoethanol and sodium hydride gives the title compound as an oily residue, which is employed in the subsequent step without further purification.

Sources & evidence

ORD record: ord-6438e4b8a6f9471a9834d3034dc8da51
Source dataset: uspto-grants-2000_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06162809

Reaction notes

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