Methyl 4-bromobenzoate → HCID 10473217, compound

HRID 1275615Notes

Reaction equation

HRID 1275615 reaction equation
[CH3:1][C:2]1[C:3]([OH:16])=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.Br[C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][CH:19]=1>>[CH3:1][C:2]1[C:3]([O:16][C:18]2[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][CH:19]=2)=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:12])([CH3:13])[C:10]=2[CH:11]=1

Participants

3

Reactant 2

HCID 12081Methyl 4-bromobenzoateHCID 2266903,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-ol

Product 1

HCID 10473217HCID 10473217, compound

Procedure

In a manner similar to Example 1(a) above, by the reaction of 1.1 g (5 mmol) of 3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthol with 0.89 g (4.1 mmol) of methyl 4-bromobenzoate, 670 mg (46%) of the expected methyl ester of melting point 133-5° C. were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-13e177f78eaa48149524165aede1df78
Source dataset
uspto-grants-2000_12
Patent number
US06162815

Reaction notes

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