Methyl 4-iodobenzoate → HCID 22117425, compound

HRID 1275620Notes

Reaction equation

HRID 1275620 reaction equation
[Br:1][C:2]1[C:3]([OH:16])=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.I[C:18]1[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][CH:19]=1>>[Br:1][C:2]1[C:3]([O:16][C:18]2[CH:27]=[CH:26][C:21]([C:22]([O:24][CH3:25])=[O:23])=[CH:20][CH:19]=2)=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:12])([CH3:13])[C:10]=2[CH:11]=1

Participants

3

Reactant 2

HCID 69273Methyl 4-iodobenzoateHCID 107793113-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ol

Product 1

HCID 22117425HCID 22117425, compound

Procedure

In the manner similar to Example 1(a), by the reaction of 1 g (3.5 mmol) of 3-bromo-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthol with 770 mg (2.94 mmol) of methyl 4-iodobenzoate, 700 mg (58%) of the expected methyl ester of melting point 135-6° C. were obtained.

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-df6f1e6929ac4804b1d8a4f18a4da11d
Source dataset
uspto-grants-2000_12
Patent number
US06162815

Reaction notes

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