Hydrochloric Acid → HCID 22480362, compound

Participants

Reaction Steps

1.3 g (5.7 mmol) of 3-(5-carboxy-2-furyl)indazole together with 1.3 g (11.4 mmol) of potassium tert-butoxide were dissolved in 5 ml of dry DMF and admixed with 2-chloro-4-trifluoromethylpyrimidine dissolved in 5 ml of DMF. The mixture was stirred at 60° C. the hydrochloride was precipitated from the aqueous phase by addition of 1N hydrochloric acid. This gave 420 mg (25%) of the title compound. m.p.: 258-261° C.

Provenance & Evidence