Sulfuric Acid → HCID 20638671, compound

HRID 1275775Notes

Reaction equation

HRID 1275775 reaction equation
[CH2:1]([C:3]1[CH:7]=[CH:6][S:5][C:4]=1[C:8]1([OH:21])[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH3:2].C[O:23][C:24](=[O:47])[C@H:25]([C@@H:44]([CH3:46])O)[NH:26]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O.OS(O)(=O)=O>FC(F)(F)C(O)=O>[CH2:1]([C:3]1[CH:7]=[CH:6][S:5][C:4]=1[C:8]1([O:21][C@H:44]([CH3:46])[C@@H:25]([C:24]([OH:47])=[O:23])[NH2:26])[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=2[C:15]2[C:20]1=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH3:2]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 11164107HCID 11164107, compoundHCID 22117601HCID 22117601, compound

Product 1

HCID 20638671HCID 20638671, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidCatalyst

Procedure

from 9-(3-ethylthien-2-yl)-9H-fluoren-9-ol and Nα -(9-fluorenylmethoxycarbonyl)-L-threonine methyl ester following method A, using trifluoroacetic acid as catalyst in place of H2SO4 ;

Sources & evidence

ORD record
ord-13705e78213742b09768e2f739666aaa
Source dataset
uspto-grants-2000_12
Patent number
US06162824

Reaction notes

Loading…