Sulfuric Acid → HCID 54236446, compound

HRID 1275777Notes

Reaction equation

HRID 1275777 reaction equation
[CH:1]1([C:6]2[CH:10]=[CH:9][S:8][C:7]=2[C:11]2([OH:24])[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:5][CH2:4][CH2:3][CH2:2]1.C[O:26][C:27](=[O:50])[C@H:28]([C@@H:47]([CH3:49])O)[NH:29]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O.OS(O)(=O)=O>FC(F)(F)C(O)=O>[CH:1]1([C:6]2[CH:10]=[CH:9][S:8][C:7]=2[C:11]2([O:24][C@H:47]([CH3:49])[C@@H:28]([C:27]([OH:50])=[O:26])[NH2:29])[C:23]3[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=3[C:17]3[C:12]2=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 11164107HCID 11164107, compoundHCID 22117526HCID 22117526, compound

Product 1

HCID 54236446HCID 54236446, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidCatalyst

Procedure

from 9-(3-cyclopentylthien-2-yl)-9H-fluoren-9-ol and Nα -(9 fluorenylmethoxycarbonyl)-L-threonine methyl ester following method A, using trifluoroacetic acid as catalyst in place of H2SO4 ;

Sources & evidence

ORD record
ord-646f846f684547ae99fc13c54cdbed5b
Source dataset
uspto-grants-2000_12
Patent number
US06162824

Reaction notes

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