Sulfuric Acid → HCID 54258490, compound

HRID 1275780Notes

Reaction equation

HRID 1275780 reaction equation
[S:1]1[C:5]([C:6]2([OH:19])[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[C:12]3[C:7]2=[CH:8][CH:9]=[CH:10][CH:11]=3)=[CH:4][C:3]2[CH:20]=[CH:21][CH:22]=[CH:23][C:2]1=2.C[O:25][C:26](=[O:49])[C@H:27]([C@@H:46]([CH3:48])O)[NH:28]C(OCC1C2C=CC=CC=2C2C1=CC=CC=2)=O.OS(O)(=O)=O>FC(F)(F)C(O)=O>[S:1]1[C:5]([C:6]2([O:19][C@H:46]([CH3:48])[C@@H:27]([C:26]([OH:49])=[O:25])[NH2:28])[C:18]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[C:12]3[C:7]2=[CH:8][CH:9]=[CH:10][CH:11]=3)=[CH:4][C:3]2[CH:20]=[CH:21][CH:22]=[CH:23][C:2]1=2

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 11164107HCID 11164107, compoundHCID 22117570HCID 22117570, compound

Product 1

HCID 54258490HCID 54258490, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidCatalyst

Procedure

from 9-(benzo[b]thien-2-yl)-9H-fluoren-9-ol (Example 2n) and UW-(9-fluorenylmethoxycarbonyl)-L-threonine methyl ester following method A, using trifluoroacetic acid as catalyst in place of H2SO4 ;

Sources & evidence

ORD record
ord-5924299b81054550a5061981737b1bcc
Source dataset
uspto-grants-2000_12
Patent number
US06162824

Reaction notes

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