HCID 53911394, compound → HCID 22117238, compound

HRID 1275898Notes

Reaction equation

HRID 1275898 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([CH:11]=[CH:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([Br:19])[CH:14]=2)[CH:3]=1.[H][H]>C1(C)C=CC=CC=1.[Pt](=O)=O>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([Br:19])[CH:14]=2)[CH:3]=1

Participants

5

Reactant 2

HCID 53911394HCID 53911394, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22117238HCID 22117238, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 1140TolueneSolvent

Procedure

The product from step (iii) (8.5 g) and platinum(iv)oxide (0.87 g) in toluene (150 ml) was stirred under 1 atmosphere of hydrogen for 72 hours. The mixture was filtered and the filtrate evaporated under reduced pressure. Yield 6. 1 g.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate evaporated under reduced pressure
  3. customYield 6

Sources & evidence

ORD record
ord-6a28f2596af24b8cb3bd18cbb0ea4dcf
Source dataset
uspto-grants-2000_12
Patent number
US06162808

Reaction notes

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