HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → 1-(Bromomethyl)-2,3-dimethylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | (2,3-Dimethylphenyl)methanol | HCID 96208 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(Bromomethyl)-2,3-dimethylbenzene | HCID 113627 | — |
Reaction Steps
A mixture of 1-hydroxymethyl-2,3-dimethylbenzene (ref) (5 g) and phosphorous tribromide (1.16 ml) in benzene (50 ml) was heated at reflux for 3 hours. The mixture was diluted with toluene, washed with water, dried (MgSO4) and evaporated. Yield 7 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162808 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-f25708848ecf4d70a9b64b1ebba36797 |
| Source note | uspto-grants-2000_12 |