HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetraethyltin → 2-ethyl-10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetraethyltin | HCID 11704 | — |
| Reactant | 2-Bromo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one | HCID 19261781 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-ethyl-10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5-one | HCID 22117289 | — |
Reaction Conditions
| Temperature | 130 °C |
|---|
Reaction Steps
A mixture of the product from step (iv) (1.52 g), tetraethyl tin (10.4 ml) and tetrakis(triphenylphosphine)palladium(0) (100 mg) in dimethylformamide (20 ml) was heated at 130° C. for 48 hours. The mixture was evaporated and the residue purified by chromatography eluting with isohexane then 50% toluene in isohexane then toluene. Yield 0.88 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06162808 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-fef0f6e46a054941975ac4b93e1e766f |
| Source note | uspto-grants-2000_12 |