反应详情

温度

130 °C

A mixture of the product from step (iv) (1.52 g), tetraethyl tin (10.4 ml) and tetrakis(triphenylphosphine)palladium(0) (100 mg) in dimethylformamide (20 ml) was heated at 130° C. for 48 hours. The mixture was evaporated and the residue purified by chromatography eluting with isohexane then 50% toluene in isohexane then toluene. Yield 0.88 g.

1. customThe mixture was evaporated
2. customthe residue purified by chromatography
3. washeluting with isohexane