反应详情

In a similar manner to the preparation of 5-(3-chloro-5-trifluoromethylpyridin-2-yl)-3-methyl-1-(1-methylethyl)benzimidazol-2-one described above, 2.5 g of 5-(3-chloro-5-trifluoromethylpyridin-2-yl)-1-(1-methylethyl)benzimidazol-2-one and 0.9 g of bromoacetonitrile gave, after chromatography on silica gel, 1.4 g of colorless crystals. Yield: 50%; m.p.: 158-159° C.

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