Picolyl chloride hydrochloride → HCID 14422702, compound

HRID 1276299Notes

Reaction equation

HRID 1276299 reaction equation
[CH2:1]([CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[CH:8][C:9]([OH:15])=[CH:10][CH:11]=2)[C:6]1=[O:16])[CH2:2][CH2:3][CH3:4].Cl.[N:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH2:24]Cl>>[CH2:1]([CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[CH:8][C:9]([O:15][CH2:24][C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][N:18]=3)=[CH:10][CH:11]=2)[C:6]1=[O:16])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 23392Picolyl chloride hydrochlorideHCID 10846487HCID 10846487, compound

Product 1

HCID 14422702HCID 14422702, compound

Procedure

By the method of Example 10, the title product of Example 9 (5.70 g, 34.3 mmol) and 2-picolyl chloride hydrochloride (5.63 g, 34.3 mmol) were converted to present title product, 4.37 g (41%), m.p. 56-60° C.

Sources & evidence

ORD record
ord-f8a4b4b9bc4643dfb8473f8f0b9c5318
Source dataset
uspto-grants-2000_12
Patent number
US06166031

Reaction notes

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