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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1276313Generated: October 30, 2026

Acetic Anhydride → 1-Acetylindolin-2-one

https://huagongshe.com/reaction/1276313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantOxindoleHCID 321710—
Product1-Acetylindolin-2-oneHCID 323719—

Reaction Steps

1,3-Dihydro-2H-indol-2-one (35.6 g, 0.268 mol) suspended in acetic anhydride (30 mls) and mixture refluxed for 20 hours. Filtered and washed with diethyl ether (50 mls) dried in vacuo at 80 deg C. to give a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06166040
Source datasetuspto-grants-2000_12
ORD IDord-26435e77b1fe4214ae645e05df9a5aa0
Source noteuspto-grants-2000_12