Acetyl chloride → HCID 70003051, compound

Participants

Reaction Steps

Acetyl chloride (3 ml) was added dropwise to a solution of 7 grams of crude 5-fluoro-2,3-dihydro--1H-indole and 3 ml of triethylamine in 100 ml of CH2Cl2 at 0° C. After two hours, the reaction was diluted with water. The methylene chloride layer was separated, dried and evaporated to afford 7.3 grams of crude product which was purified on silica gel eluting with hexane/ethyl acetate to give 3.3 grams of the titled compound.

Provenance & Evidence