Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Acetyl-5-fluoro-2,3-dihydro-1H-indole-6-sulfonic acid amide | HCID 54550645 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 54280196 | HCID 54280196 | 99.5% |
Reaction Steps
A mixture of 3.6 grams of 1-Acetyl-5-fluoro-2,3-dihydro-1H-indole-6-sulfonic acid amide and 30 ml of 2N sodium hydroxide was heated at 100° C. for 3 hours. The reaction was cooled and the pH was adjusted to 7.0 with acetic acid. The resulting precipitate was filtered to give 3.0 grams of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06166064 |
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| Source dataset | uspto-grants-2000_12 |
|---|
| ORD ID | ord-be50d3691f3c429f8f8b1f2691f14de0 |
|---|
| Source note | uspto-grants-2000_12 |
|---|
