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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12768Generated: October 30, 2026

Hydrochloric Acid → HCID 67519706, compound

https://huagongshe.com/reaction/12768

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-(3,5-dimethyl-4-isoxazolyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedioneHCID 24759236—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67519706HCID 67519706—

Reaction Steps

5-(3,5-dimethyl-4-isoxazolyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione was treated with a solution of 4N HCl in dioxane (500 μl) to give the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727988B2
Source datasetuspto-grants-2010_06
ORD IDord-efe0c6d0bf7749698b9246fbf7b93084
Source noteuspto-grants-2010_06