HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Trifluoromethyl)benzene → Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Trifluoromethyl)benzene | HCID 7368 | — |
| Reactant | Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol | HCID 64556 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | Tricyclo(3.3.1.1'3,7)dec-1-ylmethanol | HCID 64556 | — |
| Product | 1-Adamantanecarboxaldehyde | HCID 11041050 | — |
Reaction Steps
The procedure of Example 1 was repeated, except that 1 millimole of 1-hydroxymethyladamantane was used instead of 1-decanol and 6 ml of 1,2-dichloroethane was employed in lieu of trifluoromethylbenzene, to give 1-adamantanecarbaldehyde in a conversion rate of 1-hydroxymethyladamantane of 76% (yield 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06166264 |
| Source dataset | uspto-grants-2000_12 |
| ORD ID | ord-a5ef3853e2954933ad098ce51bff29da |
| Source note | uspto-grants-2000_12 |