Thiophenol → HCID 18672845, compound

HRID 1276853Notes

Reaction equation

HRID 1276853 reaction equation
Cl[C:2]1[CH:31]=[CH:30][C:5]2=[N:6][N:7]([C:9]3[CH:14]=[C:13]([C:15]([CH2:18][C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:17])[CH3:16])[CH:12]=[C:11]([C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)[C:10]=3[OH:29])[N:8]=[C:4]2[CH:3]=1.[OH-].[K+].[C:34]1([SH:40])[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>CN1CCCC1=O>[C:34]1([S:40][C:2]2[CH:31]=[CH:30][C:5]3=[N:6][N:7]([C:9]4[CH:14]=[C:13]([C:15]([CH2:18][C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:17])[CH3:16])[CH:12]=[C:11]([C:23]5[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=5)[C:10]=4[OH:29])[N:8]=[C:4]3[CH:3]=2)[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

Participants

5

Reactant 3

HCID 7969ThiophenolHCID 14797Potassium HydroxideHCID 18672841HCID 18672841, compound

Product 1

HCID 18672845HCID 18672845, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

The tide compound is prepared according to the procedure of Example 4 from 20 g of the compound of Example 8, 20.4 g of 45% aqueous potassium hydroxide, 10.3 g of thiophenol and 100 g of N-methylpyrrolidone. The title compound is an oil purified by chromatography on silica gel using toluene as eluent

Workup

  1. customThe tide compound is prepared

Sources & evidence

ORD record
ord-037adc30532b4ff181b0cc697900875e
Source dataset
uspto-grants-2000_12
Patent number
US06166218

Reaction notes

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