Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12769Generated: October 29, 2026

Hydrochloric Acid → HCID 68692768, compound

https://huagongshe.com/reaction/12769

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 24759237HCID 24759237—
ProductHCID 68692768HCID 68692768—

Reaction Steps

5-(2-methyl-4-pyridinyl)-1-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-2,4(1H,3H)-pyrimidinedione was treated with a solution of 4N HCl in dioxane (1 eq) to give the title compound as a white solid. (32 mg)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07727988B2
Source datasetuspto-grants-2010_06
ORD IDord-bfd1cb1a2e094032ba781c3474bebb44
Source noteuspto-grants-2010_06