1-Chloro-4-nitrobenzene → HCID 14998834, compound

HRID 1277325Notes

Reaction equation

HRID 1277325 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[CH3:11][O:12][CH2:13][CH2:14][NH2:15]>>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([NH:15][CH2:14][CH2:13][O:12][CH3:11])=[CH:3][CH:4]=1)([O-:10])=[O:9]

Participants

3

Reactant 2

HCID 74741-Chloro-4-nitrobenzeneHCID 80182-Methoxyethylamine

Product 1

HCID 14998834HCID 14998834, compound

Procedure

One heats to reflux for 15 hours 0.3 mole of parachloronitrobenzene (47.35 g) in solution in 150 ml of β-methoxyethylamine. One then pours the cooled reaction mixture into 300 g of crushed ice. The intended product precipitates first in the form of a red oil which crystallizes rapidly. After recrystallization in ethanol and drying under vacuum the product melts at 86° C. Analysis gives the following results:

Workup

  1. additionOne then pours
  2. customThe intended product precipitates first in the form of a red oil which
  3. customcrystallizes rapidly
  4. customAfter recrystallization in ethanol
  5. dry with materialdrying under vacuum the product melts at 86° C
  6. customAnalysis gives the
  7. customfollowing results

Sources & evidence

ORD record
ord-2b9f2570547d4a8084e2c80fedc3c884
Source dataset
uspto-grants-1981_07
Patent number
US04277244

Reaction notes

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