Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | HCID 12895629 | HCID 12895629 | — |
| Product | HCID 54369018 | HCID 54369018 | — |
Reaction Steps
The above named compound is prepared by treating 317 mg (1 mMole) of 3-[2-(1-aminoethyl)1,3-dithian-2-yl]-4,4,4-trifluoro-2-methylbutyric acid with 1.0 ml of 1 N HCl and 10 ml of acetonitrile followed by treatment with 2 ml of methyl iodide. The mixture is stirred at 25° C. for 48hours then diluted with water. The mixture is then thoroughly washed with ether and the aqueous phase is concentrated to afford 3-alanyl-4,4,4-trifluoro-2-methylbutyric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04277395 |
|---|
| Source dataset | uspto-grants-1981_07 |
|---|
| ORD ID | ord-2660ce901ba84f22a4b3e0fa38c49e45 |
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| Source note | uspto-grants-1981_07 |
|---|
