HCID 14083133, compound → HCID 23453547, compound

Participants

Reaction Steps

1-t-butyl 6-methyl 2-benzylideneamino-2-benzyl-4-benzyloxycarbonyl-4-difluoromethyl-5-methyl-3-oxohexanedioate is prepared in a similar manner except that t-butyl 3-phenyl-2-benzylideneaminopropionate is used in place of t-butyl 2-benzylideneaminopropionate and methyl 2-benzyl-3-benzyloxycarbonyl-3-chloroformyl-4,4-difluorobutanoate and methyl 3-benzyloxycarbonyl-3-chloroformyl-4,4-difluoro-2-methyl butanoate are used respectively in place of methyl 3-chloroformyl-4,4-difluoro-2-methylbutanoate.

Provenance & Evidence