Methyl iodide → HCID 86737839, compound

HRID 1277364Notes

Reaction equation

HRID 1277364 reaction equation
[C:1]1([CH:7]2[C:13]3([CH2:17][CH2:16][C:15](=[S:18])[NH:14]3)[CH:11]3[CH2:12][CH:8]2[CH:9]=[CH:10]3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:19][I:20]>CC(C)=O>[IH:20].[CH3:19][S:18][C:15]1[CH2:16][CH2:17][C:13]2([CH:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH:8]3[CH2:12][CH:11]2[CH:10]=[CH:9]3)[N:14]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 23453665HCID 23453665, compound

Product 1

HCID 86737839HCID 86737839, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

6 mmoles of 3-phenyl-spiro[bicyclo[2.2.1]-hept-5-ene-2,2'-pyrrolidine]-5'-thione are dissolved in 30 ml of acetone, 1 ml of methyl iodide is added and the mixture is refluxed for 10 minutes. After cooling, the precipitate is filtered off. The crystalline compound, which is pure according to a thin layer chromatogram, is further processed immediately.

Workup

  1. temperaturethe mixture is refluxed for 10 minutes
  2. temperatureAfter cooling
  3. filtrationthe precipitate is filtered off

Sources & evidence

ORD record
ord-ce1f6dea3c3246be9bf6ca9402bd3425
Source dataset
uspto-grants-1981_07
Patent number
US04277470

Reaction notes

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