Hydrochloric Acid → HCID 23453834, compound

HRID 1277375Notes

Reaction equation

HRID 1277375 reaction equation
[CH:1]([NH:4][CH2:5][CH:6]([OH:21])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)([CH3:3])[CH3:2].[ClH:22]>>[Cl-:22].[CH:1]([NH2+:4][CH2:5][CH:6]([OH:21])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 12944288HCID 12944288, compound

Product 1

HCID 23453834HCID 23453834, compound

Procedure

Following a precedure similar to that of Example 32, 1,2-epoxy-4-(1,1'-biphenyl-2-yl)butane was reacted with isopropylamine to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylamine. The amine base so formed was reacted with hydrogen chloride to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylaminium chloride. M.P. 153°-154° C.

Sources & evidence

ORD record
ord-ba277840df3b49028a992dc0c1c986ff
Source dataset
uspto-grants-1981_07
Patent number
US04277471

Reaction notes

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