Methylamine → 1-Nitro-2-methylamino-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

HRID 1277457Notes

Reaction equation

[N+:1]([CH:4]=[C:5](SC)[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2].[CH3:18][NH2:19]>>[N+:1]([CH:4]=[C:5]([NH:19][CH3:18])[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2]

Participants

Reactant 2

HCID 6329Methylamine

HCID 705429481-(Methylsulfanyl)-2-nitro-N-(2-{[(1,3-thiazol-2-yl)methyl]sulfanyl}ethyl)ethen-1-amine

Product 1

HCID 705418401-Nitro-2-methylamino-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

Procedure

Reaction of 1-nitro-2-methylthio-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene with methylamine according to the process of Example 8(ii) yielded the title compound, m.p. 103°-104°. (from ethanol ether).

Sources & evidence

ORD record: ord-5bcbeee78c384f50a7181a3d33c3ee1f
Source dataset: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04277485

Reaction notes

Loading…